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Filtered Search Results
Medchemexpress LLC Bradykinin acetate | 6846-03-3 | 99.6% | 1060.21 | 10 MG
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Bradykinin acetate is a potent endothelium-dependent vasodilator known for its ability to lower blood pressure. It is involved in inducing contraction of bronchial and intestinal non-vascular smooth muscle, increasing vascular permeability, and participating in pain mechanisms. This compound is suitable for various research applications, including studies on its role in cardiovascular function, inflammation, and cellular signaling pathways.
- Effective endothelium-dependent vasodilator
- Lowers blood pressure
- Induces contraction of bronchial and intestinal non-vascular smooth muscle
- Increases vascular permeability
- Participates in pain mechanisms
- Stable for 2 years at -80°C as powder
- Stable for 6 months at -80°C in solvent under sealed, moisture-free conditions
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Medchemexpress LLC Ornipressin acetate | 914453-98-8 | 99.6% | 1042.19 | 10 MG
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Ornipressin acetate (POR-8) is a potent vasoconstrictor and hemostatic agent that acts as a vasopressin agonist specific for the V1 receptor. It can be utilized as a local vasoconstrictor, can reverse hypotension associated with combined general/epidural anesthesia, and possesses antidiuretic activity. Ornipressin acetate also demonstrates the ability to decrease renal vascular resistance and increase renal blood flow in renal failure models.
- Potent vasoconstrictor
- Hemostatic and renal agent
- Vasopressin V1 receptor agonist
- Antidiuretic activity
- Decreases renal vascular resistance
- Increases renal blood flow in renal failure models
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Medchemexpress LLC BMP-4 acetate | 99.30% | 1308.52 (free base) | 50 MG
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BMP-4 acetate is a penetrating heparin-binding peptide known for its anti-inflammatory and anti-chondrogenic properties. It operates by modulating the iNOS-IFN-IL6 signaling pathway, which leads to the suppression of inflammatory proteins such as iNOS, COX2, IFN, and IL6. This mechanism helps effectively reduce inflammation and alleviate various arthritis symptoms in both murine chondrocytes and macrophages.
- Penetrating heparin-binding peptide
- Exhibits anti-inflammatory functions
- Exhibits anti-chondrogenic functions
- Regulates the iNOS-IFN-IL6 signaling pathway
- Inhibits expression of inflammatory proteins (iNOS, COX2, IFN, IL6)
- Suppresses inflammation
- Alleviates arthritis symptoms in murine chondrocytes and macrophages
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Medchemexpress LLC PNC-27 acetate | 99.9% | 4031.73 | 50 MG
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PNC-27 acetate is a chimeric p53-penetratin peptide that binds to HDM-2 in a p53 peptide-like structure. It induces selective membrane-pore formation and leads to cancer cell lysis. PNC-27 acetate is an anticancer peptide and can be used in acute myeloid leukemia research.
- Induces cancer cell death.
- Binds to cell membrane-bound HDM-2 in A2058 and MCF-7 cells.
- Shows anti-leukemia activity in mice.
- Reduces AML engraftment and prolongs survival in AML mice.
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Medchemexpress LLC Cigb-300 (acetate) | 98.0% | 3060.60 | 1 MG
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CIGB-300 acetate (P15-Tat acetate) is an anti-casein kinase 2 (CK2) peptide that exhibits anticancer properties by interfering with the phosphorylation of protein kinase CK2. CIGB-300 acetate induces apoptosis in multiple tumor cell lines and can be used in cancer research.
- Exhibits anticancer properties
- Interferes with phosphorylation of protein kinase CK2
- Induces apoptosis in multiple tumor cell lines
- Useful in cancer research
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Medchemexpress LLC OCTYL ACETATE 100G
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OCTYL ACETATE 100G
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Medchemexpress LLC Incensole Acetate | 34701-53-6 | 1 ML
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Incensole acetate is a main constituent of Boswellia carterii resin, and it has neuroprotective effects against neuronal damage in traumatic and ischemic head injury. It reduces Aβ25-35-triggered apoptosis in hOBNSCs.
- Neuroprotective effects against neuronal damage in traumatic and ischemic head injury.
- Reduces Aβ25-35-triggered apoptosis in hOBNSCs.
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Medchemexpress LLC Cedryl acetate | 77-54-3 | 99.78% | 264.40 | 1 ML
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Cedryl acetate is a tricyclic sesquiterpene isolated from the plant *Cunninghamia lanceolata* and is the analytical standard of Cedryl acetate. It shows α-glucosidase inhibitory activity and is intended for research and analytical applications.
- Tricyclic sesquiterpene
- Isolated from *Cunninghamia lanceolata*
- Shows alpha-glucosidase inhibitory activity
- Research and analytical applications
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Medchemexpress LLC Akn-028 (acetate) | 98.38% | 362.39 | 100 MG
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AKN-028 acetate is a novel tyrosine kinase (TK) inhibitor. It is a potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC50 value of 6 nM. It inhibits FLT3 autophosphorylation and induces dose-dependent cytotoxic response (mean IC50=1 μM). AKN-028 acetate induces apoptosis by activation of caspase 3 and can be used in research of acute myeloid leukemia (AML).
- Potent and orally active FLT3 inhibitor with an IC50 of 6 nM.
- Inhibits FLT3 autophosphorylation.
- Induces dose-dependent cytotoxic response with a mean IC50 of 1 μM.
- Induces apoptosis through activation of caspase 3.
- Suitable for research in acute myeloid leukemia (AML).
- Shows cytotoxic activity against AML cell lines.
- Inhibits tumor growth in xenograft models.
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Medchemexpress LLC PRT062607 acetate | 1370261-98-5 | C21H27N9O3 | 100 MG
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PRT062607 acetate is a solid chemical identified for laboratory use and substance manufacturing. It is recommended to store this product at 4°C, sealed and away from moisture. When in solvent, store at -80°C for up to 6 months or -20°C for 1 month, also sealed and away from moisture. Shipping at room temperature is acceptable for periods less than 2 weeks.
- Identified for laboratory chemicals and manufacture of substances
- Stable under recommended storage conditions
- Recommended storage at 4°C, sealed, away from moisture
- Storage in solvent at -80°C for 6 months or -20°C for 1 month, sealed, away from moisture
- Appearance: Solid
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Apexbio Technology LLC ICATIBANT-ACETATE-1MG
Icatibant Acetate (CAS No 138614-30-9) is a synthetic peptide and a selective bradykinin B2 receptor antagonist used in biomedical research for its ability to inhibit bradykinin-induced responses Originating from efforts to manage hereditary angioedema it acts by blocking the B2 receptor pathway preventing vasodilation and vascular permeability Its in vitro activity is observed in the nanomolar range It is commonly applied in cell-based assays animal models and drug screening to explore inflammatory responses and vascular permeability Experimental concentrations typically depend on the specific research design
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Apexbio Technology LLC EPTIFIBATIDE-ACETATE-50MG
Eptifibatide Acetate (CAS No 148031-34-9) is an antithrombotic agent used primarily in cardiovascular research Originating from a synthetic peptide modeled on a protein found in snake venom it functions by inhibiting platelet aggregation through blocking the glycoprotein IIb/IIIa receptor pathway on platelets This action effectively prevents fibrinogen from binding thus reducing thrombus formation Eptifibatide Acetate demonstrates in vitro activity in the nanomolar to low micromolar range which makes it suitable for various research applications including cell models animal studies and drug screening assays Its experimental concentrations typically depend on the specific research design
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Apexbio Technology LLC DEGARELIX-ACETATE-100MG
Degarelix acetate (CAS No 934016-19-0) is a gonadotropin-releasing hormone (GnRH) antagonist used in biomedical research primarily for its role in androgen deprivation therapy Originating from synthetic peptides it functions by binding to GnRH receptors in the anterior pituitary gland effectively decreasing the release of luteinizing hormone and subsequently reducing testosterone production Its in vitro activity typically ranges from the nanomolar to low micromolar concentration Degarelix acetate is commonly applied in cell models and animal studies to investigate prostate cancer treatment and it is also used in drug screening for hormonal therapies Experimental concentrations typically depend on the specific research design offering flexibility in application across various studies
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Apexbio Technology LLC CHLORMADINONE-ACETATE-100MG
Chlormadinone acetate (CAS No 302-22-7) is a synthetic progestogen commonly used in biomedical research to study hormone-related pathways Originally derived from progesterone it functions primarily by binding to progesterone receptors inhibiting ovulation and exhibiting anti-androgenic properties In vitro it shows bioactivity in the nanomolar to low micromolar range affecting cellular proliferation and gene expression in hormone-sensitive assays It is frequently utilized in cell models including breast cancer and prostate cancer lines as well as in animal studies to explore its effects on reproductive health and hormone-dependent conditions Drug screening applications often seek to understand its modulation of steroid hormone pathways Experimental concentrations typically depend on the specific research design
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Alkali Scientific Tris Acetate Ultra Pure, 100 G
Tris Acetate Ultra Pure is a high-purity buffering agent used in laboratory applications where a stable pH is required. The 100g size is suitable for preparing buffer solutions in a variety of molecular biology and biochemistry experiments. Tris Acetate is particularly useful in gel electrophoresis for nucleic acids, where it provides an optimal buffering capacity to stabilize the pH during the separation process. The high purity of this reagent ensures that it does not interfere with the analysis of proteins or nucleic acids, making it ideal for high-precision experiments. This buffering agent is widely used in research and diagnostics where reliable pH control is essential for reproducible results.
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