Fatty alcohol esters
Medchemexpress LLC Octyl acetate 250g
Octyl acetate is an orally active aliphatic ester Octyl acetate has certain antioxidant properties Octyl acetate contributes to the formation of fruit aroma and affects the flavor of fruits such as strawberries Octyl acetate can be used in the research of malignant melanoma colon cancer and breast cancer[1][2][3][4]
Apexbio Technology LLC KEMPTIDE-ACETATE-SALT-1MG
Kemptide acetate salt is a synthetic peptide used extensively in biomedical research particularly in studies involving kinase activity Originating as a substrate for protein kinase A (PKA) Kemptide s mechanism of action involves the phosphorylation of threonine residues by serine/threonine-specific kinases This phosphorylation event is crucial for studying signal transduction pathways and enzyme-substrate interactions It exhibits in vitro activity primarily in the nanomolar to low micromolar range Kemptide is commonly used in various experimental setups including cell-based assays and in vitro kinase assays to investigate enzyme kinetics and for drug screening purposes Experimental concentrations typically depend on the specific research design
Apexbio Technology LLC DEGARELIX-ACETATE-2MG
Degarelix acetate (CAS No 934016-19-0) is a gonadotropin-releasing hormone (GnRH) antagonist used in biomedical research primarily for its role in androgen deprivation therapy Originating from synthetic peptides it functions by binding to GnRH receptors in the anterior pituitary gland effectively decreasing the release of luteinizing hormone and subsequently reducing testosterone production Its in vitro activity typically ranges from the nanomolar to low micromolar concentration Degarelix acetate is commonly applied in cell models and animal studies to investigate prostate cancer treatment and it is also used in drug screening for hormonal therapies Experimental concentrations typically depend on the specific research design offering flexibility in application across various studies
Medchemexpress LLC Retinyl acetate | 127-47-9 | 328.49 | 1 ML
Retinyl acetate is a synthetic acetate ester form derived from retinol that possesses potential antineoplastic and chemopreventive activities. It is for research use only and not sold to patients.
- Purity of 99.30%
- Off-white to light yellow solid appearance
- Classified as terpenoids, diterpenoids
- Initial source is endogenous metabolite
- Shipped at room temperature in continental US
- Store powder at -20°C for 3 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
- Inhibits proliferation of tumor cells at 10 μM in vitro
- Inhibits DMBA induced mammary carcinogenesis in Sprague-Dawley rats at 250 mg/kg in diet in vivo
Apexbio Technology LLC Guanabenz Acetate 23256-50-0 50mg
Guanabenz Acetate (CAS 23256-50-0) is a small molecule that acts as a selective agonist of the 2-adrenergic receptor subtypes It exhibits notable affinity for the 2a-adrenergic receptor (pEC50 8 25) with moderate activity at the 2b-adrenergic receptor (pEC50 7 01) and lower potency at the 2c-adrenergic receptor (pEC50 5) Through activation of these receptors Guanabenz Acetate modulates adrenergic neurotransmission making it a valuable tool for investigating the physiological and pharmacological functions of 2-adrenergic signaling in biomedical research
Medchemexpress LLC Poneratoxin acetate | 2756.35 (free base) | 10 MG
Poneratoxin acetate is the acetate salt form of Poneratoxin (HY-P10234). It acts as a modulator for voltage-gated sodium channels (NaV, with EC50 for NaV1.6 and NaV1.7 being 97 nM and 2.3 μM), decreasing the voltage threshold for activation and inhibiting channel inactivation. This compound enhances the excitability of neurons and contributes to the transmission of pain signals.
- Modulator for voltage-gated sodium channels
- Lowers the voltage threshold for activation
- Inhibits the inactivation of channels
- Enhances the excitability of neurons
- Contributes to the transmission of pain signals
- For powder, store at -80°C for 2 years or -20°C for 1 year
- For solution, store at -80°C for 6 months or -20°C for 1 month
- Store sealed and away from moisture
Medchemexpress LLC CBP-501 (acetate) | 1929.06 (free base) | 1 MG
CBP-501 acetate is a cell-permeable calmodulin-binding peptide and a G2-abrogating drug candidate. It inhibits the activity of multiple Ser216-specific kinases, including MAPKAP-K2, C-Tak1, CHK1, and CHK2. It is used for various types of cancer and enhances the cytotoxicity of CDDP and Bleomycin against cancer cells both in vitro and in vivo.
- Inhibits MAPKAP-K2 with an IC50 of 0.9 μM
- Inhibits C-Tak1 with an IC50 of 1.4 μM
- Inhibits Chk1 with an IC50 of 3.4 μM
- Inhibits Chk2 with an IC50 of 6.5 μM
- Stable for 2 years at -80°C as powder
- Stable for 1 year at -20°C as powder
- Stable for 6 months at -80°C in solvent
- Stable for 1 month at -20°C in solvent
- Enhances cytotoxicity of CDDP and Bleomycin
Medchemexpress LLC Farnesyl pyrophosphate ammonium | 116057-57-9 | 95.39% | 433.42 | 1 MG
Farnesyl pyrophosphate ammonium is a metabolic intermediate in the mevalonate (MVA) pathway. It acts as a TRP channel (TRPM2) agonist, triggering Ca2+ influx and cell death. It is a crucial branch substrate for various biological syntheses and is utilized in research concerning a range of diseases.
- Acts as a TRP channel (TRPM2) agonist
- Triggers Ca2+ influx and cell death
- Key branch substrate for cholesterol synthesis
- Key branch substrate for ubiquinone synthesis
- Key branch substrate for protein farnesylation
- Key branch substrate for geranylgeranyl pyrophosphate (GGPP) synthesis
- Used in research on cerebral ischemia
- Used in research on neurodegenerative diseases
- Used in research on pancreatic cancer
- Used in research on inflammation
- Used in research on autoimmune diseases